Tetanus is a serious bacterial infection caused by Clostridium tetani. It affects the nervous system, leading to painful muscle stiffness and spasms, and can become life-threatening if untreated. The bacteria are commonly found in soil, dust, and animal feces and enter the body through cuts, wounds, or punctures. Early medical intervention is critical for effective treatment.
Symptoms usually appear within 3–21 days after injury and may include:
Main causes include:
Tetanus is diagnosed mainly through clinical evaluation, focusing on symptoms and recent injuries, as laboratory tests are not routinely used.
The biggest risk for tetanus is missing vaccination or booster shots, with other factors also increasing infection risk.
Tetanus treatment focuses on managing the infection, neutralizing the toxin, and providing supportive care:
Wound Management: Effective treatment begins with thorough cleaning and debridement of all contaminated or infected tissue. This step removes the source of bacteria and helps prevent further toxin production, reducing the severity of the infection.
Antitoxin Therapy: Tetanus immune globulin (TIG) is administered to neutralize the circulating toxin in the bloodstream. This prevents the toxin from affecting the nervous system, thereby reducing muscle stiffness and spasms.
Antibiotics: Antibiotics such as metronidazole or penicillin are used to kill any remaining Clostridium tetani bacteria at the wound site. This helps prevent further toxin release and stops the infection from progressing.
Muscle Relaxants and Sedatives: Medications are used to relieve painful muscle spasms, improve comfort, and reduce the risk of complications such as fractures or respiratory distress caused by severe contractions.
Supportive Care: Patients often require intensive monitoring in an ICU setting, especially if breathing muscles are affected. Supportive care includes airway management, ventilator support if necessary, proper nutrition, hydration, and physical therapies to assist recovery and maintain overall health.