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Rheumatoid Arthritis (RA) Treatment

Rheumatoid Arthritis (RA) Treatment In Trivandrum

Rheumatoid arthritis is a chronic autoimmune disease in which the body’s immune system attacks the joints, causing inflammation, pain, stiffness, and potential joint damage. Early diagnosis and treatment are essential to slow disease progression and maintain joint function.

Symptoms and Causes

What are the symptoms of Rheumatoid Arthritis?

Common symptoms of rheumatoid arthritis:

  • Pain and Tenderness.
  • Swelling.
  • Stiffness.
  • Fatigue.
  • Fever.
  • Loss of Appetite and Weight Loss.
  • Joint Deformities.
  • Nodules.

What causes Rheumatoid Arthritis?

RA occurs when the immune system mistakenly targets joint tissues. Key factors include:

  • Autoimmune Response: The immune system attacks the synovium (lining of the joints), leading to inflammation and tissue damage.
  • Genetic Factors: Family history and specific genes, such as HLA-DR4, can increase susceptibility.
  • Environmental Triggers: Smoking, infections, or other environmental exposures may contribute to disease onset.

Diagnosis of Rheumatoid Arthritis

At our hospital, rheumatoid arthritis (RA) is diagnosed using a combination of clinical evaluation, lab tests, and imaging for accurate assessment:

  • Medical History & Physical Exam: Doctors evaluate joint pain, stiffness, swelling, and symmetry, along with functional limitations and morning stiffness.
  • Blood Tests: Tests for rheumatoid factor (RF), anti-CCP antibodies, and inflammation markers (ESR, CRP) help confirm diagnosis and assess disease activity.
  • Imaging Tests: X-rays, ultrasound, or MRI detect joint erosion and inflammation, guiding treatment and monitoring progression.

What are the Rheumatoid Arthritis risk factors?

Certain factors increase the likelihood of developing RA:

  • Age: RA most commonly develops between 30 – 60 years, though it can occur at any age. Risk increases as people get older.
  • Gender: Women are 2–3 times more likely than men to develop RA, possibly due to hormonal and immune system differences.
  • Family History: A family history of RA or certain genetic markers (like HLA-DR4) can increase susceptibility, suggesting a hereditary component.
  • Lifestyle Factors: Smoking and obesity are linked to higher RA risk. Smoking may trigger immune system changes, and excess weight increases joint stress and inflammation.
  • Other Autoimmune Diseases: Individuals with conditions such as lupus or Sjögren’s syndrome may have a higher likelihood of developing RA,  due to an already overactive immune system.

What treatment options are available for Rheumatoid Arthritis?

Our hospital provides a multidisciplinary approach to manage RA and improving the quality of life:

Medication: Medications are the cornerstone of rheumatoid arthritis management, aimed at reducing pain, controlling inflammation, and slowing disease progression. Nonsteroidal anti-inflammatory drugs (NSAIDs) help relieve pain and decrease inflammation, while corticosteroids are used for short-term control during acute flare-ups. Disease-modifying antirheumatic drugs (DMARDs), such as methotrexate, hydroxychloroquine, or leflunomide, work to slow the progression of the disease and prevent joint damage. In more advanced cases, biologic therapies target specific immune system pathways to reduce inflammation and protect joints from further harm.

Therapies and supportive care: Therapies and supportive care play a vital role in managing rheumatoid arthritis and maintaining quality of life. Physical therapy focuses on improving joint mobility, strength, and flexibility, helping to reduce stiffness and prevent further disability. Occupational therapy assists patients in adapting daily activities and using supportive devices to preserve independence and function. Additionally, lifestyle measures such as maintaining a balanced diet, engaging in regular exercise, managing weight, and reducing stress can help control symptoms and support overall joint health.

Advanced Cases: In advanced cases of rheumatoid arthritis where joints are severely damaged, surgical options may be considered to restore function and relieve pain. Procedures such as joint replacement or synovectomy can help improve mobility, reduce discomfort, and enhance quality of life when medications and conservative therapies are no longer sufficient.